Methicillin-resistant Staphylococcus Aureus
Do you want clear detection and differentiation of: S. aureus, mecA, mecC, PVL-Toxin and BlaZ?
MRSA can affect anyone! Staphylococcus aureus is one of the most important pathogens for nosocomial infections. In its resistant form as MRSA, due to the difficulty of treating it, it constitutes a significant risk factor for affected patients and occurs in hospitals all over the world.
There are also forms of MRSA that are completely independent of hospitals and that are often also resistant to the antibiotic fusidic acid. These germs are known as CA-MRSA (community-acquired MRSA) and also have a special pathogenicity factor (Panton-Valentine-leukocidine, encoded by the lukS-lukF gene).
cMRSA occurs entirely independently of hospitals. Due to a special pathogenicity factor (PVL-Panton-Valentine leukocidin) cMRSA has the particular ability to form multiple, recurrent, deep abscesses as well as pneumonia with a necrotising, often fatal, outcome. This PVL-Toxin, which is characteristic for cMRSA, is encoded by the ® lukS-lukF gene and is detectable with the eazyplex MRSAplus in 15 min.
There are also forms of MRSA that are completely independent of hospitals and that are often also resistant to the antibiotic fusidic acid. These germs are known as CA-MRSA (community-acquired MRSA) and also have a special pathogenicity factor (Panton-Valentine-leukocidine, encoded by the lukS-lukF gene).
cMRSA occurs entirely independently of hospitals. Due to a special pathogenicity factor (PVL-Panton-Valentine leukocidin) cMRSA has the particular ability to form multiple, recurrent, deep abscesses as well as pneumonia with a necrotising, often fatal, outcome. This PVL-Toxin, which is characteristic for cMRSA, is encoded by the ® lukS-lukF gene and is detectable with the eazyplex MRSAplus in 15 min.
MRSA, MRSA but with different targets & MRSA but it detects different targets again
eazyplex® MRSA
With the eazyplex® MRSA, there is clear detection of:
eazyplex® MRSAplus
This kit offers the detection of mecA, mecC and PVL toxin gene targets. Due to a special pathogenicity factor (PVL-Panton-Valentine leukocidin) cMRSA has the particular ability to form multiple, recurrent, deep abscesses as well as pneumonia with a necrotising, often fatal, outcome. The eazyplex® MRSAplus is used from bacterial culture and provides clear detection of the targets within 15 minutes from culture. Furthermore, the eazyplex® MRSAplus provides clear evidence of:
eazyplex® MRSAexpert
The β-lactamase (bla) locus, which confers resistance to penicillins only, may control the transcription of mecA, the central element of methicillin resistance, which is embedded in a polymorphic heterelogous chromosomal cassette (the SCCmec element. The eazyplex® MRSAexpert provides clear evidence of:
With the eazyplex® MRSA, there is clear detection of:
- S. aureus,
- MecA,
- MecC
- S. epidermidis.
eazyplex® MRSAplus
This kit offers the detection of mecA, mecC and PVL toxin gene targets. Due to a special pathogenicity factor (PVL-Panton-Valentine leukocidin) cMRSA has the particular ability to form multiple, recurrent, deep abscesses as well as pneumonia with a necrotising, often fatal, outcome. The eazyplex® MRSAplus is used from bacterial culture and provides clear detection of the targets within 15 minutes from culture. Furthermore, the eazyplex® MRSAplus provides clear evidence of:
- S. aureus
- MecA
- MecC
- PVL-Toxin
eazyplex® MRSAexpert
The β-lactamase (bla) locus, which confers resistance to penicillins only, may control the transcription of mecA, the central element of methicillin resistance, which is embedded in a polymorphic heterelogous chromosomal cassette (the SCCmec element. The eazyplex® MRSAexpert provides clear evidence of:
- S. aureus
- MecA
- MecC
- PVL-Toxin
- blaZ
A graph for the graph-inclined of you
*Wowe!* I hear you say, "a graph? for me?"
Yes it's just for you - don't show anyone else okay - this pretty colour graph showcases what your results look like when running eazyPlex tests on an eazyMini. The graph is plotted in real-time so you can watch the spike as it happens!
Yes it's just for you - don't show anyone else okay - this pretty colour graph showcases what your results look like when running eazyPlex tests on an eazyMini. The graph is plotted in real-time so you can watch the spike as it happens!
The Amplex eazyPlex system
Amplex eazyplex® panels, the eazyplex® panels are a selection of kits with different targets to aid your specific diagnostic needs which include:
- Meningitis
- Enterics
- Healthcare-Associated Infections (HAIs)
- Multi-drug Resistance involving Gram-Negative bacteria
- Sepsis
- Respiratory Infections
- Sexually Transmitted Infections (STIs)
Features
- 5 min sample pretreatment
- No DNA extraction
- Variable device selection
- Real-Time-Detection
- Lyophilised tests
- Turn around time - under 30 minutes
Did you know? If you purchase an Amplex eazyMini, you open the door to a wide range of LAMP diagnostics, with TATs under 30 minutes
Introducing Amplex eazyplex® LAMP assays to your hospital opens the door to a wide range of molecular diagnostics.
For example in under 30 minutes the eazyplex®Blood Screen will provide first steps in your ?septicaemia case. The range of assays include others that all require urgent action such as meningitis, STIs, ARMs, Candida auris etc.
For example in under 30 minutes the eazyplex®Blood Screen will provide first steps in your ?septicaemia case. The range of assays include others that all require urgent action such as meningitis, STIs, ARMs, Candida auris etc.
The Manufacturer
Amplex Diagnostics GmbH is a German-based company founded in 2002 that specialises in providing rapid and robust CE-IVD tests to aid the diagnosis of microbiological infections. One of their products was the world's first MRSA multiplex PCR test to be CE IVD-certified for testing directly from sample material.
Amplex makes the latest advanced technology available in a simple and user-friendly manner. Their eazyplex® system which can be operated intuitively, combines isothermal amplification (LAMP) with real-time detection. The eazyplex® reagents are supported by the eazyMini which enables isothermal amplification of all DNS and RNA targets in one compact device. It was specially developed for isothermal amplification assays with real-time detection based on fluorescence and enables reading of molecular diagnostics Real-time detection within a few minutes.
www.eazyplex.com
Amplex makes the latest advanced technology available in a simple and user-friendly manner. Their eazyplex® system which can be operated intuitively, combines isothermal amplification (LAMP) with real-time detection. The eazyplex® reagents are supported by the eazyMini which enables isothermal amplification of all DNS and RNA targets in one compact device. It was specially developed for isothermal amplification assays with real-time detection based on fluorescence and enables reading of molecular diagnostics Real-time detection within a few minutes.
www.eazyplex.com