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WELCOME! WELCOME!

That's right we're back, returning from our may hiatus (I was too busy organising and redesigning the catalogue page) to talk to you about Microbiologics' range of multiplex QC panels for Cepheid GeneXpert and the BioFire film array panels.

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As you can see, we're talking about five specific panels that have a range of targets and are intended for use with specific panels and instruments. To break it down for you:


For the Cepheid Xpert GI Panel:

  • #8267: GI Verification Panel (Pellet) - 11 Targets. Negative Control - Patient relevant matrix.
  • #8248: GI Control Panel (Swab) - 11 Targets. Negative Control - Patient relevant matrix.

For the BioFire BCID2 Panel:

  • #8254: BCID Control Panel (Pellet) - 43 Targets. Negative Control - Blank pellet.

For the BioFire respiratory 2.1 Panel:

  • #8247: Respiratory Control Panel (Pellet) - 22 Targets. Negative Control - Blank Pellet.

For the BioFire Gastrointestinal panel:

  • #8236: GI Control Panel (Pellet) - 22 Targets. Negative Control - Blank pellet.
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System-Specific Panels

For more information of the specific targets of each panel, please follow this link

Here!

Why you should use third-party controls in your lab

Within clinical laboratories, it is important to ascertain and maintain the highest possible standards of accuracy and reliability in test performance.


Therefore, routine internal quality control checks are integral to this process and are performed daily, sometimes multiple times per day, weekly or monthly.


This routine QC ensures the precision and reliability of both analytical instruments and their reagents. Some key benefits to using third-party controls are as follows:

  • They allow for the independent and unbiased assessment of instruments and method performance.
  • They are highly consolidated QC materials, this means that the laboratory can save time, space and costs by combining multiple controls into a single, efficient solution.
  • Compliance with ISO 15189 is a point that is always spoken about, especially when UKAS visits are incoming. The use of third-party QCs helps laboratories meet these stringent regulatory and accreditation requirements, ensuring high standards of practice.
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So why choose Microbiologics?

In their own words, Microbiologics "maximises the advantages of external controls by engineering QC products to resemble patient samples in the manner of sample collection and handling".


Their controls are available as lyophilised swab and pellet formats, with their molecular controls designed to be processed as if they were patient samples. They have a vast portfolio for the KWIK-STIKs alone, including the major syndromic groups of infectious disease. Chances are if you are looking for a control, whether it's syndrome, or system, specific, Microbiologics have a control for it.

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Welcome welcome! 👋
It's a new week, so it's a new BioConnections post! This week we're talking blood culture identification (BCID). BCID is covered mainly by Microbiologics and their QC panels, but you'll never guess what! We supply our own Fastidious Anaerobe Agar (F.A.A) for culturing your positive blood cultures on!

Blood Culture Identification 

This week i’m excited to highlight two innovative solutions that are helping clinical and research laboratories streamline workflows and improve diagnostic accuracy. The Microbiologics BCID Panel offers a reliable, quality-controlled way to verify molecular blood culture identification systems, ensuring confidence in rapid pathogen detection when time matters most. 

Complementing this, BioConnections (our own) FAA Agar provides a high-performance medium for the cultivation of fastidious anaerobes, supporting consistent growth and reproducible results. Together, these tools empower laboratories to maintain the highest standards in microbiological testing while enhancing efficiency and patient outcomes.

Microbiologics 

First up we have Microbiologics (Who have a product for just about everything) and their Blood Culture Identification control panel (with 43 targets)
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This nifty little panel comes with 6 positive control 1's, 6 positive control 2's and 6 negative controls. The make-up for each positive control is listed below for your convenience. BCID control panels are essential tools for ensuring the accuracy and reliability of blood culture identification systems used in clinical microbiology. These quality control materials are designed to monitor every stage of molecular diagnostic workflows, including extraction, amplification, and detection, helping laboratories identify variability, validate assay performance, and maintain compliance with regulatory standards.
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For the eagle-eyes among you, you will have noticed I've also included Microbiologics' Gram-positive and Gram-negative blood culture control panels that come as inactivated pellets. The Gram-Positive Blood Culture Control Panel includes 3 pools containing 3-4 inactivated microorganisms per pool. Kits contain 5 vials of each pool (15 total vials) and feature colour coordinated labels for easy pool identification.

The Gram-Negative Blood Culture Control Panel also includes 3 pools containing 3-5 inactivated microorganisms per pool. Kits contain 5 vials of each pool (15 total vials) and feature colour coordinated labels for easy pool identification.

BioConnections

OMG looks it's us! We made it into a blog post!
Yes your eyes are working correctly, We offer our own F.A.A agar for you to pour your own plates. These plates have one of the same benefits as CHROMagar dehydrated media (if you think back to last week), it has a super long shelf-life! It comes in either 500g or 2.5kg that can be sent to you!
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Our F.A.A agar has been around for quite some time (longer than I've been alive lol) and has been referenced in reports dating back to 1995. One of the main sources I could dig up was this Bordatella petrii Clinical Isolate article that used our agar to culture a bone biopsy specimen in 2005.

​Our medium also has the option to be made selective with the addition of antibiotic supplements. This is the medium of choice for the routine isolation of clinically significant anaerobes, our medium supports the growth of most fastidious anaerobes. Classical colony formation, odour and fluorescence under UV are diagnostic features on this medium. The choice of peptones and growth factors provide early growth of most organisms whilst the starch has an important role as a de-toxification agent. The medium is often made selective for various groups of anaerobes by the addition of appropriate selective agents.

That's all for this week! Next week we're going to talk about STI and women's health (HPV screening and such)

Welcome to the BioConnections Blog!

This is the official blog for BioConnections news on products and updates, information can also be found on our LinkedIn and the emails we send to you every Wednesday!
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Author

Callum Wood

I have a dog.