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Neo-Sensitabs – no ordinary sensitivity disc

ASM MIcrobe - Stable Antibiotic Sensitivity Disks  DOI: https://doi.org/10.1128/AAC.9.5.848
ABSTRACT 'Two methods of preparing sensitivity disks were compared for their effect on disk stability at 25 and 37 C. One method consisted of applying a solution of the antibiotic to blank disks by the conventional procedure; the second method consisted of applying the antibiotic to the disks as a suspension of crystals. Of the four β-lactam antibiotics that were studied, disks made with suspended crystals were substantially more stable than corresponding disks made by the conventional method.'
Does stability mean better results?
A multi centre evaluation in UK hospitals showed good comparison between paper discs and Rosco tablets with 'stable' antibiotics but significantly better results obtained with Rosco tablets when the antibiotic was less stable (co-amoxyclav).
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Do I need to refrigerate Rosco Neo-Sensitabs?
Most Neo-Sensitabs are stable at room temperature for a number of years, a few of the more labile antibiotics should be refrigerated for long term storage. However even the more labile antibiotics are stable at room temperature for 2 months which means in most cases working stock will not need refrigeration on a daily basis as is the case with paper discs.
Why are most Neo-Sensitabs stable at room temperature?
Unlike paper discs we use the dry crystalline antimicrobial which is compacted into tablets.

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  • Home page
  • Contact BioConnections
  • MolecularControls
  • CoVID Controls
  • REFERENCE STRAINS
  • Parasitology
  • Eazyplex® Range
    • eazyplex® AMR
    • eazyplex® C. difficle
    • eazyplex® BloodScreen
    • eazyplex® TyphiTyper
    • eazyplex® VRE
    • eazyplex® EHEC
    • eazyplex® STI
    • eazyplex® CSFdirect
    • eazyplex® MRSA
    • eazyplex® PneumobBug
    • eazyplex Pneumocystis jirovecii
    • eazyplex® hv-K. pneumoniae
  • MBLO blog