Gram negative AST - Amplex has developed the eazyplex® SuperBug range to give wider faster coverage.
Introducing the eazyplex® SuperBug AMR sets for mainstream diagnostics and for rare resistances
Introducing the eazyplex® SuperBug AMR sets for mainstream diagnostics and for rare resistances
Resistance to antibiotics in Gram negative pathogens is nothing new, but our emphasise must be on rapid testing to support clinicians in antimicrobial stewardship.
eazyplex® CRE provides direct confirmation from a positive blood culture in 15 minutes, it will also give results from rectal swabs, positive blood culture and urine in 20 minutes or under. Both carbapenemases and ESBLs are included.
We should also be aware of new threats just round the corner. SuperBug tests are available to cover less common resistances like common resistance genes such as GIM, GES and AmpC genotypes CMYII , DHA and MOX.
eazyplex® CRE provides direct confirmation from a positive blood culture in 15 minutes, it will also give results from rectal swabs, positive blood culture and urine in 20 minutes or under. Both carbapenemases and ESBLs are included.
We should also be aware of new threats just round the corner. SuperBug tests are available to cover less common resistances like common resistance genes such as GIM, GES and AmpC genotypes CMYII , DHA and MOX.
Where we are today - overnight culture then test for the big 4 or 5
eazyplex® Complete A, B, and C are three options that cover the most frequently occurring carbapenemases.
Complete C delivers cover of the UK's Big 5; plus OXA181, which has been reported increasingly worldwide. Results from the culture plate are delivered in under 30 minutes.
eazyplex® Basic covers 4 of the UK's current Big 5 plus OXA181. Results from a culture colony are delivered in under 30 minutes.
eazyplex® Complete A, B, and C are three options that cover the most frequently occurring carbapenemases.
Complete C delivers cover of the UK's Big 5; plus OXA181, which has been reported increasingly worldwide. Results from the culture plate are delivered in under 30 minutes.
eazyplex® Basic covers 4 of the UK's current Big 5 plus OXA181. Results from a culture colony are delivered in under 30 minutes.
Where we could be now – the big 4 and key β-lactamases direct from the sample in 20 minutes
eazyplex® CRE delivers direct screening from rectal swab and urine in 20 minutes, and confirmation from a positive blood culture and culture plate in 15 minutes.
eazyplex® CRE covers; KPC, NDM, OXA48, VIM. and OXA181 plus β-lactamases CTX-M-1 and CTX-M-9.
eazyplex® CRE delivers direct screening from rectal swab and urine in 20 minutes, and confirmation from a positive blood culture and culture plate in 15 minutes.
eazyplex® CRE covers; KPC, NDM, OXA48, VIM. and OXA181 plus β-lactamases CTX-M-1 and CTX-M-9.
What we should be aware of – threats round the corner
OXA variants /AmpCs: ACC, CMY II, DHA, MOX / IMP IMI GES GIM
eazyplex® Expert is a confirmatory test for rare carbapenemases in Enterobacteriaceae, Pseudomonads, and Acinetobacter. The sample is taken from a cultured colony. Results are delivered in under 30 minutes
eazyplex® Acineto, with this eazyplex® you can detect the OXA variants OXA51, OXA23 , OXA40 and OXA58-like, and NDM in just 15 minutes. The sample is colony from an agar plate, optimally selective media
eazyplex® AmpC can differentiate the following AmpC groups as culture confirmation.
AmpCs: ACC, CMY II, DHA, and MOX.
Results from the culture colony are delivered in under 30 minutes.
OXA variants /AmpCs: ACC, CMY II, DHA, MOX / IMP IMI GES GIM
eazyplex® Expert is a confirmatory test for rare carbapenemases in Enterobacteriaceae, Pseudomonads, and Acinetobacter. The sample is taken from a cultured colony. Results are delivered in under 30 minutes
eazyplex® Acineto, with this eazyplex® you can detect the OXA variants OXA51, OXA23 , OXA40 and OXA58-like, and NDM in just 15 minutes. The sample is colony from an agar plate, optimally selective media
eazyplex® AmpC can differentiate the following AmpC groups as culture confirmation.
AmpCs: ACC, CMY II, DHA, and MOX.
Results from the culture colony are delivered in under 30 minutes.
Published References
To date, there are 15 published references to the eazyplex SuperBug range of products.
6 cite both Carbapenemases and ESBLs
2 cite Blood Culture
2 cite Urine
4 cite Acineto
1 cites Carbapenemases and Hypervirulence-Associated Genes
Details of these references are available on our website at https://bit.ly/4b7R3N6
examples
'The eazyplex® SuperBug CRE assay can be a useful tool for a rapid (less than 20 min) and reliable identification of resistance mechanism genes in Gram negative rods and also directly from urine and pre-cultured blood samples.'
'eazyplex® SuperBug Acineto test is a rapid (15–30 min) and reliable test for the detection of the most common carbapenemases observed in Acinetobacter spp. and for species determination of A. baumannii.'
To date, there are 15 published references to the eazyplex SuperBug range of products.
6 cite both Carbapenemases and ESBLs
2 cite Blood Culture
2 cite Urine
4 cite Acineto
1 cites Carbapenemases and Hypervirulence-Associated Genes
Details of these references are available on our website at https://bit.ly/4b7R3N6
examples
'The eazyplex® SuperBug CRE assay can be a useful tool for a rapid (less than 20 min) and reliable identification of resistance mechanism genes in Gram negative rods and also directly from urine and pre-cultured blood samples.'
'eazyplex® SuperBug Acineto test is a rapid (15–30 min) and reliable test for the detection of the most common carbapenemases observed in Acinetobacter spp. and for species determination of A. baumannii.'