Due to intrinsic resistance to numerous antibiotics (e.g. cephalosporins, clindamycin, trimethoprim-sulfamethoxazole and low concentrations of aminoglycosides), enterococci, as pathogens of nosocomial infections, have gained enormously in importance in recent years.
The eazyplex VRE system delivers information about VanA or VanB resistance in 20 min, whether from rectal swabs, blood culture or as culture confirmation, without DNA-extraction, including all necessary controls.
The eazyplex VRE system delivers information about VanA or VanB resistance in 20 min, whether from rectal swabs, blood culture or as culture confirmation, without DNA-extraction, including all necessary controls.
eazyplex® VRE and eazyplex® VREbasic
Features
eazyplex®VRE - Detection and reliable identification of VRE (Vancomycin resistant enterococci) in rectal or wound swab, bacterial colonies as well as positive blood cultures
eazyplex®VRE basic - Detection of VRE (Vancomycin-resistant enterococci) from bacterial colonies as well as from positive blood cultures
Amplification curve of a VRE test with the eazyplex® system.
The screen shows the amplified target sequences (here vanA), the human sample control and the inhibition control. For maximum reliability of results and avoidance of false negative results, the kit for direct testing from swabs contains a combination of bacterial and human controls. The eazyplex® VREbasic Kit as a pure culture confirmation test of agar plates and positive blood cultures is as cost-effective as possible.
Features
- Lyophilised tests
- 5 min sample pretreatment
- Variable device selection
- No DNA extraction
- Real-Time-Detection
eazyplex®VRE - Detection and reliable identification of VRE (Vancomycin resistant enterococci) in rectal or wound swab, bacterial colonies as well as positive blood cultures
eazyplex®VRE basic - Detection of VRE (Vancomycin-resistant enterococci) from bacterial colonies as well as from positive blood cultures
Amplification curve of a VRE test with the eazyplex® system.
The screen shows the amplified target sequences (here vanA), the human sample control and the inhibition control. For maximum reliability of results and avoidance of false negative results, the kit for direct testing from swabs contains a combination of bacterial and human controls. The eazyplex® VREbasic Kit as a pure culture confirmation test of agar plates and positive blood cultures is as cost-effective as possible.
Buying into the Amplex eazyplex® system opens the door to a wide range of infectious disease diagnostics,
The eazyplex® system is an advanced molecular diagnostics platform that uses loop-mediated amplification (LAMP) technology for rapid and sensitive pathogen detection with a user-friendly interface.
The eazyplex® system is an advanced molecular diagnostics platform that uses loop-mediated amplification (LAMP) technology for rapid and sensitive pathogen detection with a user-friendly interface.
Amplex eazyplex® panelsThe eazyplex® panels are a selection of kits with different targets to aid your specific diagnostic needs which include:
eazyplex® Gram Negatives
Resistance to antibiotics in gram-negative pathogens is nothing new. Nevertheless, there is a need for tests not only for common resistances such as KPC, NDM and CTX-M, but also for resistance genes, such as GIM and GES or AmpC, which are still rare at the moment, in order to ensure a complete diagnosis. For this we have developed the eazyplex® SuperBug series for you.
eazyplex®VRE
Screen without DNA extraction directly from the swab with eazyplex® VRE - you will have clarity in about 20 minutes. The quick examination of positive blood cultures also reliably contributes to a good therapy decision.
eazyplex® STD
STDs travel overnight, Stop it now!
eazyplex® STD has 3 panels to detect the most common sexually transmitted bacteria in 25 minutes optimised with different parameters to fit your diagnostic requirements.
eazyplex® Blood Screen
Early diagnosis and prompt, appropriate clinical therapy for sepsis are critical to increasing the chances of survival. Antibiotic resistance is a key factor determining clinical responsiveness to treatment and rapid disease progression in sepsis and septic shock. With eazyplex® BloodScreen Gram-positive and Gram-negative panel you can detect the most common bacterial pathogens of sepsis and associated antibiotic resistances, which strongly influence the outcome of the disease.
eazyplex® CSF direct
The eazyplex® CSF direct has 3 panels with optimised parameter selection to differentiate bacterial and viral causes of meningitis to test directly from cerebrospinal fluid (CSF) with results in 30 minutes to improve survival outcomes as mortality significantly increases with delayed therapy and reduce the use of empiric therapy.
eazyplex® C. difficile
The eazyplex® C. difficile panel allows the detection of C.diff all in one step or confirmatory tests for the presence of toxin. This kit has 3 panels to allow detection of Toxin B only, GDH & toxin or GDH, Toxin A, Toxin B and Binary Toxin directly from stool in 25 minutes!
eazyplex® TyphiTyper
The eazyplex® TyphiTyper enables the differentiation of Salmonella in 20 minutes without the time-consuming agglutination tests.
eazyplex® Candida Auris
Candida auris, an insidious fungal pathogen continues to be a global health concern with it's ability to spread rapidly, persist in healthcare settings and defy conventional treatments. This fungus often eludes traditional laboratory methods leading to misidentification or delayed detection. The eazyplex® Candida auris allows direct diagnosis from culture or swabs in 25 minutes.
eazyplex® EHEC
Work with your desired combination of parameters and differentiate between: • EHEC • EPEC • EIEC • EAEC directly from the stool sample or as a culture confirmation with just one test in 25 minutes.
eazyplex® MRSA
The eazyplex® MRSA kit has 2 panels and with the combination of the two test kits eazyplex® MRSA and eazyplex® MRSAplus you have the complete solution for your MRSA diagnostics. Whether as an examination directly from the screening swabs in 20 minutes or as a detection from positive blood cultures or from agar plates in 15 minutes
eazyplex® PneumoBug
Direct diagnostics from BAL, bronchial and tracheal secretions in 25 minutes With eazyplex® PneumoBug expert you have reliable help for your diagnostics.
- Meningitis
- Enterics
- Healthcare-Associated Infections (HAIs)
- Multi-drug Resistance involving Gram-Negative bacteria
- Sepsis
- Respiratory Infections
- Sexually Transmitted Infections (STIs)
eazyplex® Gram Negatives
Resistance to antibiotics in gram-negative pathogens is nothing new. Nevertheless, there is a need for tests not only for common resistances such as KPC, NDM and CTX-M, but also for resistance genes, such as GIM and GES or AmpC, which are still rare at the moment, in order to ensure a complete diagnosis. For this we have developed the eazyplex® SuperBug series for you.
eazyplex®VRE
Screen without DNA extraction directly from the swab with eazyplex® VRE - you will have clarity in about 20 minutes. The quick examination of positive blood cultures also reliably contributes to a good therapy decision.
eazyplex® STD
STDs travel overnight, Stop it now!
eazyplex® STD has 3 panels to detect the most common sexually transmitted bacteria in 25 minutes optimised with different parameters to fit your diagnostic requirements.
eazyplex® Blood Screen
Early diagnosis and prompt, appropriate clinical therapy for sepsis are critical to increasing the chances of survival. Antibiotic resistance is a key factor determining clinical responsiveness to treatment and rapid disease progression in sepsis and septic shock. With eazyplex® BloodScreen Gram-positive and Gram-negative panel you can detect the most common bacterial pathogens of sepsis and associated antibiotic resistances, which strongly influence the outcome of the disease.
eazyplex® CSF direct
The eazyplex® CSF direct has 3 panels with optimised parameter selection to differentiate bacterial and viral causes of meningitis to test directly from cerebrospinal fluid (CSF) with results in 30 minutes to improve survival outcomes as mortality significantly increases with delayed therapy and reduce the use of empiric therapy.
eazyplex® C. difficile
The eazyplex® C. difficile panel allows the detection of C.diff all in one step or confirmatory tests for the presence of toxin. This kit has 3 panels to allow detection of Toxin B only, GDH & toxin or GDH, Toxin A, Toxin B and Binary Toxin directly from stool in 25 minutes!
eazyplex® TyphiTyper
The eazyplex® TyphiTyper enables the differentiation of Salmonella in 20 minutes without the time-consuming agglutination tests.
eazyplex® Candida Auris
Candida auris, an insidious fungal pathogen continues to be a global health concern with it's ability to spread rapidly, persist in healthcare settings and defy conventional treatments. This fungus often eludes traditional laboratory methods leading to misidentification or delayed detection. The eazyplex® Candida auris allows direct diagnosis from culture or swabs in 25 minutes.
eazyplex® EHEC
Work with your desired combination of parameters and differentiate between: • EHEC • EPEC • EIEC • EAEC directly from the stool sample or as a culture confirmation with just one test in 25 minutes.
eazyplex® MRSA
The eazyplex® MRSA kit has 2 panels and with the combination of the two test kits eazyplex® MRSA and eazyplex® MRSAplus you have the complete solution for your MRSA diagnostics. Whether as an examination directly from the screening swabs in 20 minutes or as a detection from positive blood cultures or from agar plates in 15 minutes
eazyplex® PneumoBug
Direct diagnostics from BAL, bronchial and tracheal secretions in 25 minutes With eazyplex® PneumoBug expert you have reliable help for your diagnostics.
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The Genie Platforms for eazyplex®
Genie® II and the Genie® HT are the current models. The compact Genie II is a light and robust device for rapid individual tests 24/7. The device has two heating blocks. The blocks can be controlled independntly of each other and thus offer maximum flexibility. The Genie® HT is a modular upgrade with the option of 1 up to 12 independant working blocks for high throghput settings. Two processing devices are currently available with interesting developments following. The ingenious Genie® allows you to carry out fast and highly sensitive molecular diagnostics of DNA and RNA. This powerful and extremely flexible platform enables isothermal amplification of all DNA and RNA targets in one compact device. It was specially developed for isothermal amplification assays with real-time detection based on fluorescence. |
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The manufacturer
Amplex Diagnostics GmbH is a German-based company founded in 2002 that specialises in providing rapid and robust CE-IVD tests to aid the diagnosis of microbiological infections. One of their products was the world's first MRSA multiplex PCR test to be CE IVD-certified for testing directly from sample material. 
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Amplex makes the latest advanced technology available in a simple and user-friendly manner. Their eazyplex® system which can be operated intuitively, combines isothermal amplification (LAMP) with real-time detection. The eazyplex® reagents are supported by the Genie platforms which enables isothermal amplification of all DNS and RNA targets in one compact device. It was specially developed for isothermal amplification assays with real-time detection based on fluorescence and enables reading of molecular diagnostics Real-time detection within a few minutes. www.eazyplex.com |
Purchase of an Amplex Genie opens the door to a wide range of LAMP diagnostics, offering TATs under 30 minutes
Introducing Amplex eazyplex® LAMP assays to your hospital opens the door to a wide range of molecular diagnostics.
For example in under 30 minutes the eazyplex®Blood Screen will provide first steps in your ?septicaemia case. The range of assays include others that all require urgent action such as meningitis, STIs, ARMs, Candida auris etc.
Introducing Amplex eazyplex® LAMP assays to your hospital opens the door to a wide range of molecular diagnostics.
For example in under 30 minutes the eazyplex®Blood Screen will provide first steps in your ?septicaemia case. The range of assays include others that all require urgent action such as meningitis, STIs, ARMs, Candida auris etc.
