Antimicrobial Resistance Library
Detection of resistance mechanisms
Why are most Neosensitabs room temperature stable?
Unlike paper discs Neosensitabs contain compacted crystalline antibiotics.
98008 ESBL +AmpC Screen Kit
98014 Total ESBL Confirm Kit
98019 Total ESBL _AmpC Confirm Kit
Rosco kits are compliant with the EUCAST guidelines. All products are required by the ESBL & AmpC phenotyping algorithm are available in kit form.
Unlike paper discs Neosensitabs contain compacted crystalline antibiotics.
98008 ESBL +AmpC Screen Kit
98014 Total ESBL Confirm Kit
98019 Total ESBL _AmpC Confirm Kit
Rosco kits are compliant with the EUCAST guidelines. All products are required by the ESBL & AmpC phenotyping algorithm are available in kit form.
Carbapenemases
Tackling antimicrobial resistance 2019 to 2024: addendum to the UK's 5-year national action plan
GOV.UK Published 16 May 2022
GOV.UK Published 16 May 2022
- more specific, measurable, achievable, realistic and time-bound (SMART)
- reflect lessons learned from the coronavirus (COVID-19) pandemic
- reflect progress that has already been made against ambitions to reduce antibiotic prescribing in food-producing animals
- work towards new sector targets
|
Commercial assays for the detection of acquired carbapenemases The report strongly recommends the implementation of an assay for the detection of the ‘big 4’ carbapenemases in frontline diagnostic laboratories. May 2019 |
Rapid detection of Carbapenemases from Blood Cultures
Improving the blood culture pathway – Executive summary A national review of blood culture pathway processes to support better antimicrobial stewardship and improved patient safety. NHS England Version 1, 29 June 2022
'Optimising the blood culture pathway is essential in ensuring the best outcomes for patients with sepsis and in providing the most effective antimicrobial stewardship programs.' '..improved speed of detection of positive blood cultures, resulting in: improved antimicrobial stewardship (AMS), improved outcomes from sepsis, early identification of a specific organism, supporting a more accurate infection diagnosis, guiding specific investigations and further management, and early identification of infection control and public health implications.'
'Optimising the blood culture pathway is essential in ensuring the best outcomes for patients with sepsis and in providing the most effective antimicrobial stewardship programs.' '..improved speed of detection of positive blood cultures, resulting in: improved antimicrobial stewardship (AMS), improved outcomes from sepsis, early identification of a specific organism, supporting a more accurate infection diagnosis, guiding specific investigations and further management, and early identification of infection control and public health implications.'
UK GOV Policy Paper Tackling antimicrobial resistance 2019 to 2024: addendum to the UK's 5-year national action plan
Link - http://bit.ly/3WJahRx Published 16 May 2022
Halve healthcare associated Gram-negative bloodstream infections (GNBSIs)
"Introduce 4 new commitments to reduce urinary tract infections (UTIs), in support of the national action plan ambition to halve healthcare associated Gram-negative bloodstream infections (GNBSIs) by 2024. These commitments reflect the fact that UTIs are a common pathway to GNBSI."
" Establish the IPC and care standards developed in Scotland (and already adopted in Wales) as the national standards in England, to be measured annually by the regulators." Commitment retained
Link - http://bit.ly/3WJahRx Published 16 May 2022
Halve healthcare associated Gram-negative bloodstream infections (GNBSIs)
"Introduce 4 new commitments to reduce urinary tract infections (UTIs), in support of the national action plan ambition to halve healthcare associated Gram-negative bloodstream infections (GNBSIs) by 2024. These commitments reflect the fact that UTIs are a common pathway to GNBSI."
" Establish the IPC and care standards developed in Scotland (and already adopted in Wales) as the national standards in England, to be measured annually by the regulators." Commitment retained
How are patients screened for CPE in Scotland?
National Infection Prevention and Control Manual
Toolkit for the early detection, management and control of carbapenemase- producing Enterobacteriaceae in Scottish acute settings. Read more
National Infection Prevention and Control Manual
Toolkit for the early detection, management and control of carbapenemase- producing Enterobacteriaceae in Scottish acute settings. Read more
Application and clinical impact of the RESIST-4 O.K.N.V. rapid diagnostic test for carbapenemase detection in blood cultures and clinical samples. Eur J Clin Microbiol Infect Dis. 2021
'The RDT provided reliable results in less than 30 min, both on culture-grown colonies as well as on pellets from positive blood cultures. Most importantly, carbapenemase detection always led to a treatment modification'. Read more
'The RDT provided reliable results in less than 30 min, both on culture-grown colonies as well as on pellets from positive blood cultures. Most importantly, carbapenemase detection always led to a treatment modification'. Read more
Blood Culture Pathway - Royal College of Pathologists
Bulletin 201 January 2023
Antimicrobial resistance (AMR) must be a core part of clinical leadership and Trust governance. Read more
Bulletin 201 January 2023
Antimicrobial resistance (AMR) must be a core part of clinical leadership and Trust governance. Read more
UK Standards for Microbiology Investigations Investigation of blood cultures (for organisms other than Mycobacterium species)
Bacteriology | B 37 | Issue no: 8.2 | Issue date: 05.09.19 |(Under Review)
Summary table 2: Analytical standards7-11 Results of the following identification and sensitivity tests (if performed) should be completed within the following time frames from flagging positive:
Bacteriology | B 37 | Issue no: 8.2 | Issue date: 05.09.19 |(Under Review)
Summary table 2: Analytical standards7-11 Results of the following identification and sensitivity tests (if performed) should be completed within the following time frames from flagging positive:
